Arman Moini Jazani

Postdoctoral Associate

Education

09/2015- 07/2021 PhD: Chemistry

Advisor:  Jung Kwon Oh

Thesis: Multi-location acidic pH/reduction responsive degradable polymers for drug delivery                                                                                         
Concordia University, Montreal, Canada

09/2010- 12/2012 B.Sc. (Honours): Biochemistry and Molecular Biology 

Thesis: Cadmium-induced activation of Bcl-2-associated death promoter (BAD) in embryonic limb bud cells

Trent University, Peterborough, Canada

Publications

1. Kriti Kapil, Arman Moini Jazani, Grezegorz Szczepeniak, Michael R. Martinez, Adma Gorczynski, Hironobu Murata, and Krzysztof Matyjaszewski. Well-Defined hydrophilic hyperbranched polyacrylates enabled by visible-Light-mediated controlled radical branching polymerization. Macromolecules, 2024, https://doi.org/10.1021/acs.macromol.4c00408

2. Arman Moini Jazani, Hironobu Murata, Martin Cvec, Anna Lewandownska-Andralojc, Kriti Kapil, Xiaolei Hu, Ferdinando De luca Bossa, Grezegorz Szczepeniak, and Krzysztof Matyjaszewski. Aqueous photo-RAFT polymerization under ambient conditions: synthesis of protein-polymer hybrids in open air. Chemical Science, 2024, https://doi.org/10.1039/D4SC01409J.

3. Arman Moini Jazani and Krzysztof Matyjaszewski. Visible light induced photo-radical ring opening copolymerization of thionolactone and acrylates. Polymer, 2024, 302, 127032.

4. Arman Moini Jazani, Caroline Rawl, and Krzysztof Matyjaszewski. Photo-RDRP for everyone: Smartphone light-induced oxygen-tolerant reversible deactivation radical polymerization. European Polymer Journal, 2024, 202, 112631.

5. Xiaolei Hu, Grzegorz Szczepaniak, Anna Lewandowska-Andralojc, Jaepil Jeong, Bingda Li, Hironobu Murata, Rongguan Yin, Arman Moini Jazani, Subha R. Das, and Krzysztof Matyjaszewski. Red-light-driven atom transfer radical polymerization for high-throughput polymer synthesis in open air. Journal of American Chemical Society, 2023, 145, 44, 24315–24327.

6. Martin Cvek, Arman Moini Jazani, Julian Sobieski, Thaiskang Jamatia, and Krzysztof Matyjaszewski. Comparison of mechano- and photoATRP with ZnO nanocrystals. Macromolecules, 2023, 56, 5101-5110.

7. Arman Moini Jazani, Kriti Kapil, Grzegorz Szczepaniak, Hironobu Murata, Mateusz Olszewski, and Krzysztof Matyjaszewski. Fully oxygen-tolerant visible-light-Induced ATRP of acrylates in water: toward synthesis of protein-polymer hybrids. Macromolecules, 2023, 56, 5, 2017–2026.
8. Kriti Kapil, Grzegorz Szczepaniak, Michael R. Martinez, Hironobu Murata, Arman Moini Jazani, Jaepil Jeong, Subha R. Das, Krzysztof Matyjaszewski. Visible-light-mediated controlled radical branching polymerization in water. Angewandte Chemie International Edition, 2023, 62, 202217658.
9. Arman Moini Jazani, Dirk J. Schild, Julian Sobieski, Xiaolei Hu, Krzysztof Matyjaszewski. Visible light-ATRP driven by tris(2-pyridylmethyl)amine (TPMA) impurities in the open Air. Macromolecular Rapid Communications, 2022, 2200855.
10. Dirk J. Schild, Juliana Bem, Grzegorz Szczepaniak, Arman Moini Jazani, Krzysztof Matyjaszewski. Blue-light-induced atom transfer radical polymerization enabled by iron/copper dual catalysis, Journal of Polymer Science, 2022;1–9.
11. Antonina Simakova, Saadyah Averick, Arman Moini Jazani and Krzysztof Matyjaszewski. Controlling size and surface chemistry of cationic nanogels by inverse microemulsion ATRP, Macromolecular Chemistry and Physics, 2022, 2200210.
12. Arman Moini Jazani and Jung Kwon Oh. Synthesis of multiple stimuli-responsive degradable block copolymers via facile carbonyl imidazole-induced postpolymerization modification, Polymer Chemistry, 2022, 13, 4557-4568.
13. Moonhyun Choi, Arman Moini Jazani, Jung Kwon Oh and Seung Man Noh. Perfluorocarbon nanodroplets for dual delivery with ultrasound/GSH-responsive release of model drug and passive release of nitric oxide, Polymers, 2022, 14, 2240.
14. Arman Moini Jazani, Newsha Arezi, Chaitra Shetty, Jung Kwon Oh. Shell-Sheddable/Core-Degradable ABA Triblock Copolymer Nanoassemblies: Synthesis via RAFT and Concurrent ATRP/RAFT Polymerization and Drug Delivery Application, Molecular Pharmaceutics, 2021, 19, 1786-1794.
15. Xiaolei Hu, Arman Moini Jazani, and Jung Kwon Oh. Recent advances in development of imine-based acid-degradable polymeric nanoassemblies for intracellular drug delivery, Polymer, 2021, 230, 124024.
16. Arman Moini Jazani, Chaitra Shetty, Hourieh Movasat, Kamaljeet K. Bawa and Jung Kwon Oh. Imidazole-mediated dual location disassembly of acid-degradable intracellular drug delivery block copolymer nanoassemblies, Macromolecular Rapid Communications, 2021, 2100262.
17. Ge Zhang, Twinkal Patel, Pothanagandhi Nellepalli, Shubham Bhagat, Hanees Hase, Arman Moini Jazani, Ingo Salzmann, Zhibin Ye and Jung Kwon Oh. Macromolecularly engineered thermoreversible heterogeneous self‐healable networks encapsulating reactive multidentate block copolymer‐stabilized carbon nanotubes, Macromolecular Rapid Communications, 2021, 200514.
18. Yuhang Huang, Arman Moini Jazani, Elliot P. Howell, Lisa Reynolds, Jung Kwon Oh and Matthew G. Moffitt. Microfluidic shear processing control of biological reduction stimuli-responsive polymer nanoparticles for drug delivery, ACS Biomaterials Science & Engineering, 2020, 6, 9, 5069-5083.
19. Arman Moini Jazani and Jung Kwon Oh. Development and disassembly of single and multiple acid-cleavable block copolymer nanoassemblies for drug delivery, Polymer Chemistry, 2020, 11, 2934-2954.
20. Kamaljeet K. Bawa, Arman Moini Jazani, Zhibin Ye, Jung Kwon Oh. Synthesis of degradable PLA-based diblock copolymers with dual acid/reduction-cleavable junction, Polymer, 2020, 194, 122391.
21. Keaton Maruya-Li, Chaitra Shetty, Arman Moini Jazani, Newsha Arezi, Jung Kwon Oh. Dual reduction/acid-responsive disassembly and thermoresponsive tunability of degradable double hydrophilic block copolymer, ACS Omega, 2020, 5, 3734–3742.
22. Yuhang Huang, Arman Moini Jazani, Elliot P. Howell, Jung Kwon Oh, Matthew G. Moffitt. Controlled microfluidic synthesis of biological stimuli-responsive polymer nanoparticles. ACS Applied Materials and Interface, 2020, 12, 1, 177-190.
23. Arman Moini Jazani, Newsha Arezi, Chaitra Shetty, Sunghwa Hong, Haowen Li, Xiangtao Wang, Jung Kwon Oh. Tumor-targeting intracellular drug delivery based on dual acid/reduction-degradable nanoassemblies with ketal interface and disulfide core locations. Polymer Chemistry, 2019, 10, 2840-2853.
24. Kamaljeet K. Bawa, Arman Moini Jazani, Chaitra Shetty and Jung Kwon Oh. PLA-based triblock copolymer micelles exhibiting dual acidic pH/reduction responses at dual core and core/corona interface location. Macromolecular Rapid Communications, 2018, 39, 1800477.
25. Arman Moini Jazani, Newsha Arezi, Keaton Maruya-Li, Sungmin Jung, Jung Kwon Oh. Facile strategies to synthesize dual location dual acidic pH/ reduction-responsive degradable block copolymers bearing acetal/disulfide block junctions and disulfide pendants. ACS Omega, 2018, 3, 8980- 8991.
26. Arman Moini Jazani and Jung Kwon Oh. Dual location, dual acidic pH/reduction-responsive degradable block copolymer: synthesis and investigation of ketal linkage instability under ATRP conditions. Macromolecules, 2017, 50, 9427-9436.

Awards and Honors

1. B3X postdoctoral research scholarship renewal ($ 55,000), Fonds de Recherche du Québec (FRQNT), QC, Canada (2023-2024).
2. B3X postdoctoral research scholarship ($ 110,000), Fonds de Recherche du Québec (FRQNT), QC, Canada (2021-2023).
3. Concordia conference and exposition award ($ 920.2), Concordia University, QC, Canada (2021).
4. Concordia accelerator award ($ 5,000), Concordia University, QC, Canada (2021).
5. Concordia conference and exposition award ($ 981.44), Concordia University, QC, Canada (2019).
6. Oral presentation award in Macromolecular Science and Engineering Division (MSED) ($ 300), Canadian Chemistry Conference and Exhibition (CSCE), QC, Canada (2019).
7. B2X doctoral research scholarship ($ 77,000), Fonds de Recherche du Québec (FRQNT), QC, Canada (2019-2023).
8. Alexander graham bell postgraduate scholarships-doctoral program ($ 105,000), Natural Science and Engineering Council of Canada (NSERC), QC, Canada (2019-2022).
9. Mitacs Globalink research award ($ 6,000), Mitacs Canada, Beijing, China (2018).
10. Faculty of arts and science graduate fellowship ($ 24,000), Concordia University, QC, Canada (2018-2021).
11. Outstanding poster award ($ 500), Canadian Society of Pharmaceutical Science (CSPS), QC, Canada (2017).
12. Outstanding poster award, Canadian High Polymer Forum (CHPF), ON, Canada (2016).
13. Triskelion fellowship in chemistry ($ 5,000), Concordia University, QC, Canada (2016-2017).
14. Concordia conference and exposition award ($ 626.88), Concordia University, QC, Canada (2016).
15. Trent international student scholarship ($1,000), Trent University, ON, Canada (2011).
16. Member of Dean’s honour roll, Trent University, ON, Canada (2011-2012)

Presentations

1. Arman Moini Jazani. Controlling Degradation of CRP Polymers. 50^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, March 25^th-26^th 2024. (oral)
2. Arman Moini Jazani. How α-ketocarboxylates enhance control of CRP? 49^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, October 9^th-10^th 2023. (oral)
3. Arman Moini Jazani. Oxygen tolerant ATRP powered by light. 48^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, April 3^rd-4^th 2023. (oral)
4. Arman Moini Jazani. Fast and oxygen tolerant ATRP for biohybrids synthesis. 47^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, October 13^th-14^th 2022. (oral)
5. Arman Moini Jazani. Polymer protein hybrids. 46^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, March 28^th-29^th 2022. (oral)
6. Arman Moini Jazani. Branched polymer conjugates with proteins. 45^th Controlled Radical Polymerization (CRP) consortium, Pittsburgh, USA, October 18^th-19^th 2021. (oral)
7. Arman Moini Jazani. Development and disassembly of dual location acid-degradable intracellular drug delivery block copolymer nanoassemblies. Macromolecular Science and Engineering Division (MSED) of Canadian Society of Chemistry (CSC), February 25^th, 2021. (Invited talk)
8. Arman Moini Jazani and Jung Kwon Oh. Dual acidic pH- and glutathione-responsive degradable polymeric micelles for anti-cancer drug delivery. Worlds Biomaterial Congress (WBC, Online), Glasgow, Scotland, December 11^th-15^th 2020. (oral)
9. Arman Moini Jazani and Jung Kwon Oh. Synthesis of PEG-disulfide-PLA block copolymers. Advance polymeric materials Inc. Montreal, QC, Canada, July 3^rd, 2019. (oral for industry)
10. Yuhang Huang, Arman Moini Jazani, Jung Kwon Oh, Mathew Moffitt. Microfluidic control of structure and drug delivery properties of biological stimuli-responsive block copolymer nanoparticles. 102^nd Canadian Chemistry Conference (CSC), Quebec City, QC, Canada, June 3^rd-7^th 2019. (oral)
11. Arman Moini Jazani and Jung Kwon Oh. Dual location acid-degradable polymeric micelles with self-accelerating hydrolysis properties. 102^nd Canadian Chemistry Conference (CSC), Quebec, Canada, June 3^rd-7^th 2019. (oral)
12. Arman Moini Jazani and Jung Kwon Oh. Reactive copolymer-stabilized aluminum oxide nanoparticles: a proof-of-concept for development of robust self-healable heterogeneous crosslinked networks. Dural Inc. Montreal, QC, Canada, December 17^th, 2018. (oral for industry)
13. Arman Moini Jazani and Jung Kwon Oh. Synthesis of well-defined, multi stimuli responsive degradable amphiphilic block copolymer via combining ATRP and RAFT polymerization: Toward dual reduction and acidic pH labile shell-sheddable micelles. 2^nd Annual symposium of Quebec Center for Advanced Materials (QCAM-CQMF), Montreal, QC, Canada, May 3^rd-4^th, 2018. (oral)
14. Arman Moini Jazani and Jung Kwon Oh. Dual location-dual stimuli responsive degradable platform of block copolymer nanoassemblies for tumor-targeting intracellular delivery. NorthernChem Inc. Niagara Falls, ON, Canada, March 13^th, 2018. (oral for industry)
15. Arman Moini Jazani and Jung Kwon Oh. Smart nanomedicines with dual location dual stimuli-responsive polymeric nanoassemblies exhibiting location-specific degradation and enhanced drug release. 1^st Annual symposium of Quebec Center for Advanced Materials (QCAM), Sherbrooke, QC, Canada, October 23^rd-24^th, 2017. (oral)
16. Arman Moini Jazani, Keaton Maryu-Li and Jung Kwon Oh. Exploration of a new strategy utilizing ATRP to synthesize dual location dual acidic pH/reduction-responsive degradable block copolymer. 1^st Annual symposium of Quebec Center for Advanced Materials (QCAM), Sherbrooke, QC, Canada, October 23^rd-24^th, 2017. (poster)
17. Arman Moini Jazani and Jung Kwon Oh. Dual location dual acidic pH/glutathione-responsive block copolymer strategy for precise control of drug release and cellular uptake. 100^th Canadian Chemistry Conference (CSC), Toronto, Canada, May 28^th-June 1^st, 2017. (poster)
18. Arman Moini Jazani and Jung Kwon Oh. Dual reduction/acidic pH-responsive block copolymer micelles: synthesis, self-assembly and stimuli responsive enhanced release. Canadian Society for Pharmaceutical Science/Canadian Chapter of the Controlled Release Society (CSPS/CC-CRS) Conference, Montreal, Canada, May 10^th-12^th, 2017. (poster)
19. Arman Moini Jazani and Jung Kwon Oh. Dual location dual reduction/pH-responsive degradable block copolymer micelles for enhanced cellular uptake and drug-controlled release. 37^th Canadian High Polymer Forum (CHPF), Gananoque, ON, Canada, August 9^th-11^th, 2016. (poster)
20. Arman Moini Jazani and Jung Kwon Oh. Multi-location multiple stimuli-responsive degradation (ML-MSRD) of block copolymer-based micelles for rapid and controlled release. CSCAS/CQMF Advanced Materials Annual Meeting, Montreal, QC, Canada, May 3^rd-4^th, 2016. (poster)